Pericentral Nucleus Of Inferior Colliculus


GABA immunoreactivity was expressed by small, medium and large neurons and distributed in the central nucleus and the pericentral nucleus of the inferior colliculus.  

Immunoreactive cell bodies containing neurokinin B were observed, for example, in the locus coeruleus, the dorsal motor nucleus of the vagus, the median division of the dorsal nucleus of the raphe, the lateral tegmental field, the pericentral nucleus of the inferior colliculus, the internal division of the lateral reticular nucleus, the inferior central nucleus, the periaqueductal gray, the postpyramidal nucleus of the raphe, and in the medial nucleus of the solitary tract.  

The neuroanatomical study of the connections between the central nucleus of the inferior colliculus and the periaqueductal gray matter showed neuronal fibers with varicosities and with terminal bottons, both in the pericentral nucleus of the inferior colliculus and in ventral and dorsal parts of caudal aspects of the periaqueductal gray matter..  

The inferior colliculus (IC) of the bank vole is made up of 3 nuclei: the external and pericentral nucleus, which are located on the outer border of the IC, and the central nucleus, which is the largest part of IC and shows a laminated structure.  

Cholecystokinin-like immunoreactive (CCK-LI) neurons are observed in the pericentral nucleus, the external nucleus and the dorsomedial part of the central nucleus of the cat's inferior colliculus. The largest number of CCK-LI cell bodies is observed in the caudal part of the pericentral nucleus.  

Perikarya containing galanin were only found, at a low density, in the nucleus of the brachium of the inferior colliculus and in the pericentral nucleus of the inferior colliculus. A moderate density of immunoreactive fibers was observed in the periaqueductal gray, locus coeruleus, marginal nucleus of the brachium conjunctivum and below the facial nucleus, whereas a low density of such fibers was found in the nucleus of the brachium of the inferior colliculus, pericentral nucleus of the inferior colliculus, nucleus incertus, medial division of the dorsal nucleus of the raphe, accessory dorsal tegmental nucleus, Kölliker-Fuse nucleus, lateral tegmental field, postpyramidal nucleus of the raphe, pericentral division of the dorsal tegmental nucleus, infratrigeminal nucleus, medial nucleus of the solitary tract, spinal trigeminal tract, dorsal motor nucleus of the vagus, and in the lateral reticular nucleus.  

A moderate or low density of immunoreactive cell bodies was observed in the nucleus of the brachium of the inferior colliculus, pericentral nucleus of the inferior colliculus, ventral nucleus of the lateral lemniscus and in the external division of the lateral reticular nucleus. The periaqueductal gray, brachium of the inferior colliculus, nucleus of the brachium of the inferior colliculus, locus coeruleus, nucleus incertus, Kölliker-Fuse nucleus, facial nucleus, medial nucleus of the solitary tract and the area postrema contained a moderate density of immunoreactive fibres, whereas the pericentral nucleus of the inferior colliculus, nucleus sagulum, cuneiform nucleus, dorsal nucleus of the raphe, superior central nucleus, central, lateral and paralemniscal tegmental fields, ventral nucleus of the lateral lemniscus, dorsal tegmental nucleus, postpyramidal nucleus of the raphe, nucleus ambiguus, accessory dorsal tegmental nucleus, dorsal motor nucleus of the vagus and the inferior olive had the lowest density of immunoreactive fibres..  

It projects to the deep layers of the superior colliculus, the pericentral nucleus of the inferior colliculus and to the ventral nucleus of the basilar pons.  

Postsynaptic field potentials (PSFP) were recorded in the superficial layer of the pericentral nucleus (PN) by stimulating the deep layer of the PN.  

Extracellular recordings from 91 cells of the pericentral nucleus (ICP) of the inferior colliculus of the cat revealed that 83 of them were responsive to auditory stimuli and the other 8 to visual stimuli.  

By means of the modified Co-GOD method, CRFI cells were detected in almost all the subdivisions of the IC, including the dorsomedial part of the central nucleus, the ventrolateral part of the central nucleus, the pericentral nucleus and the external nucleus.  

Responses recorded from the dorsomedial division of the central nucleus of the inferior colliculus, the pericentral nucleus of the inferior colliculus, and less commonly in the medial division of the medial geniculate body were also clearly present and nearly identical during the onset of the auditory stimulus, but were sometimes consistently different for detection and nondetection conditions during the latter part of the auditory stimulus.  

A moderate number of degenerating synaptic boutons (DSB) in the pericentral nucleus of the inferior colliculus (IC) were identified electron microscopically following contralateral eye enucleation in adult cats. The present report provides evidence for a crossed retinofugal monosynaptic excitatory tract innervating the IC pericentral nucleus, a possible audio-visual integrative subcortical center..  

Two units were located in the pericentral nucleus and two in the dorsal nucleus of the lateral lemniscus.  

The major inputs to the caudodorsal nucleus (DC) stem from nucleus sagulum and the pericentral nucleus of the inferior colliculus (ICP).  

Fibers near the midline spread out as a flat sheet within the pericentral nucleus of the inferior colliculus. The optic axons travel through the dorsal pericentral nucleus and some reach the posterior pericentral nucleus, but their numbers diminish along the route, suggesting that the fibers terminate. The fact that a similar pathway was observed in rodent and primate suggests that the retino-pericentral nucleus pathway exists in other mammals..  

Tritiated leucine injections confined to the pericentral nucleus of the inferior colliculus resulted in the appearance of dense grain clusters distributed over the outer fusiform cell and molecular layers of the ipsilateral dorsal cochlear nucleus. Dense grain clusters were also evident after these injections but they appeared to result from the concomitant injection into the overlying pericentral nucleus. The results indicate that the pericentral nucleus and the more dorsal region of the central nucleus of the inferior colliculus establish overlapping connections with the outermost fusiform cell and molecular layers of the dorsal cochlear nucleus.  

It was established that the neurons of the inferior colliculus are produced between days E14 and the perinatal period in an orderly sequence: the earliest generated cells are situated rostrally, laterally and ventrally in the principal nucleus, the latest generated cells are situated caudally, medially and dorsally in the pericentral nucleus.  

The efferent projections of the central nucleus of the inferior colliculus (ICC) and the pericentral nucleus of the inferior colliculus (ICP) were examined by placing restricted injections of anterograde tracers at electrophysiologically defined loci in the inferior colliculus (IC) of the cat.  

The posterior cap of IC, regarded as the pericentral nucleus of IC (PC), projects ipsilaterally to the ventral part of the caudal tip of MGB and the posterior part of the suprapeduncular nucleus.  

The projection of loci in AI to the caudal aspect of the IC was in the form of sheets of terminals in the dorsomedial division of the central nucleus bilaterally and the pericentral nucleus ipsilaterally. The topography of projection with respect to the cochleotopic organizaton of AI appeared to be in register with the described cochleotopic organization of the central nucleus and the pericentral nucleus. The projection from AII was to the lateral (ipsilateral) and medial (bilateral) aspects of the pericentral nucleus..  

Evidence was found for broader tuning curves to occur in the pericentral nucleus compared with the central nucleus, as has been observed in the adult.  


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