Studies with both antibodies revealed a widespread topographic distribution of CCK(2)R-like immunoreactivity (CCK(2)R-LI) in regions such as cortex, olfactory bulb, nucleus accumbens, septum, striatum, hippocampus, basolateral amygdala, habenula, hypothalamus, thalamus, ventral mesencephalon, inferior colliculus, parabrachial nucleus, pontine nucleus, supercolliculus, red nucleus, subcommisural and occulomotor nucleus, area postrema, solitary, olivary, cochlear, cuneate and trigeminal nuclei and spinal cord dorsal horn in agreement with the results of previous receptor autoradiography.. 
This also applies for a few other structures such as the nucleus accumbens, substantia nigra pars reticulata, central gray matter, occulomotor nucleus and cerebellum.
In the trigeminal motor nucleus, the facial nucleus and the spinal accessory nucleus, the majority of serotonergic varicosities also appeared to contain substance P; in the occulomotor nucleus and the hypoglossal nucleus the numbers of double-labeled and single-labeled serotonergic varicosities were roughly equal.
Immunoreactive cell bodies were found in the telencephalon, diencephalon, and mesencephalon in areas as yet uncharacterized as discrete nuclei in birds (E-1, E-2, E-3, E-4, E-5); further cells were located in the diencephalic nucleus spiriformis lateralis, the midbrain medial intercollicular nucleus (E-6), the nucleus mesencephalicus lateralis, pars dorsalis, the Edinger-Westphal nucleus and dorsal occulomotor nucleus; and in the nucleus of cranial nerve X and an uncharacterized area in the dorsolateral medulla (E-7).
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