In the brainstem, CGRPi perikarya were present in the Nucleus mesencephalicus nervi trigemini, the nucleus tegmenti ventralis, the locus coeruleus, the nucleus linearis caudalis and in the parabrachial region. 
The most instructive counterpart was documented by extreme poor storage manifestations in the large neuronal perikarya of the Nucleus mesencephalicus nervi trigemini.
Tectal efferents and the efferents of the nucleus praetectalis profundus project bilaterally, the nucleus praetectalis superficialis, Nucleus mesencephalicus nervi trigemini, torus semicircularis, nucleus Darkschewitsch, and nucleus fasciculi longitudinalis medialis project ipsilaterally to the medulla oblongata. The Nucleus mesencephalicus nervi trigemini, nucleus fasciculi longitudinalis medialis, and tectal efferents reach the rostral medulla spinalis.
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