We examined this hypothesis by briefly disrupting the functions of attention-related regions in the intraparietal sulcus (IPS) using transcranial magnetic stimulation (TMS). 
To directly assess the issue of reciprocal inhibition, we used fMRI to localize those brain regions active during attention-based visual tracking and then applied low-frequency repetitive transcranial magnetic stimulation over identified areas in the left and right intraparietal sulcus to asses the behavioral effects on visual tracking.
BACKGROUND: In non-human primates grasp-related sensorimotor transformations are accomplished in a circuit involving the anterior intraparietal sulcus (area AIP) and both the ventral and the dorsal sectors of the premotor cortex (vPMC and dPMC, respectively).
At the same time, responses increased in mask-specific subregions in dorsal visual areas in and around the intraparietal sulcus.
When observers attended to the depth, the stimulus with the interocular delay produced more activity than the 2D stimulus in a large variety of cortical areas, including V1, V3A, caudal intraparietal sulcus (cIPS), and MT.
Here we show, using Granger causality measures on blood oxygen level-dependent time series, that frontal eye field (FEF) and intraparietal sulcus (IPS) activity predicts visual occipital activity before an expected visual stimulus.
A left-lateralized fronto-parietal network, including the intraparietal sulcus, the precuneus, and the dorsal prefrontal cortex, was more active during numerical comparison than during perceptual recognition. Furthermore, whole-brain regression analysis showed that activity in the left intraparietal sulcus was systematically related to the effect of numerical distance on accuracy.
In addition SPP showed a significantly weaker activation in the left fusiform gyrus, left dorsolateral prefrontal cortex, and bilateral intraparietal sulcus as compared to HC.
We found that the bilateral anterior intraparietal sulcus (aIPS), an area previously linked to the control of visually-guided grasping, along with other areas of the intraparietal sulcus, the left supramarginal gyrus (SMG) and the right mid superior parietal lobe (mid-SPL) showed clear adaptation following both repeated grasps and repeated objects.
Abstract The frontal eye fields (FEF) and the anterior intraparietal sulcus (aIPS) are involved in the control of voluntary attention in humans, but their functional differences remain poorly understood.
Functional MRI studies have demonstrated hypofunction immediately adjacent to, and anterior to, the intraparietal sulcus, a region in which structural brain differences had been identified.
Only a subset of these areas, namely, the posterior part of the dorsal intraparietal sulcus, higher-order premotor regions, and the anterior insula showed increased activation as a function of stimulus orientation. Parity judgments elicited greater activation in the right than in the left ventral intraparietal sulcus, but there were no hemispheric differences in orientation-dependent activation, suggesting that neither hemisphere is dominant for mental rotation per se.
Using fMRI, we examined effective connectivity among five left hemisphere regions of interest: fusiform gyrus (FG), inferior frontal gyrus (IFG), intraparietal sulcus (IPS), lateral temporal cortex (LTC), and medial frontal gyrus (MeFG).
Recent imaging studies have shown that the human posterior parietal cortex (PPC) contains four topographically organized areas along the intraparietal sulcus (IPS1-IPS4).
When compared with zooming out, zooming in differentially implicated left anterior intraparietal sulcus (IPS), which may reflect the functional specificity of left anterior IPS in focusing attention on local object features.
We used high frequency repetitive transcranial magnetic stimulation (rTMS) to assess the necessity for the short-term retention of spatial information of brain areas identified by previous functional imaging studies: dorsolateral prefrontal cortex (dlPFC), frontal eye fields (FEF), superior parietal lobule (SPL) and intraparietal sulcus (IPS).
Patient 1 presents a lesion in areas of the postcentral sulcus, Patient 3 in areas of the superior parietal lobule and adjacent intraparietal sulcus, and Patient 2 lesions in both regions. The involvement of Brodmann areas 4a, 4p, 3a, 3b, 1, 2, and areas IP1 and IP2 of the intraparietal sulcus was assessed in terms of the voxel overlap between the spatially transformed lesion masks and the 50%-isocontours of the cytoarchitectonic maps.
The contrast between imitation and non-matching actions was associated with activation in areas previously associated with imitation and "mirror neuron" functioning, including insula, intraparietal sulcus, dorsal premotor cortex, and superior temporal gyrus.
We observed four findings: (1) while most of the brain areas that were activated by conflict tasks showed interference effects, the intraparietal sulcus was the only region activated for both interference and facilitation components.
Several days after two-hour training, passive viewing of the same stimuli additionally activated the premotor area, intraparietal sulcus, and a visual area near the junction of the (left) intraparietal and transverse occipital sulci, demonstrating plastic changes in neuronal responsivity to the stimuli that contained indications of nigan.
According to these authors, the posterior superior parietal lobe on both hemispheres underpins the attentional orientation on the putative mental number line, the horizontal segment of the intraparietal sulcus is bilaterally related to the semantic of the numerical domain, whereas the left angular gyrus subserves the verbal knowledge of numbers.
Imagery of objects activates occipito-temporal structures, spatial transformations and mental rotation the parietal cortex (specifically the intraparietal sulcus).
Solving integrals activated a left-lateralized cortical network including the horizontal intraparietal sulcus, posterior superior parietal lobe, posterior cingulate gyrus, and dorsolateral prefrontal cortex.
Areas in the intraparietal sulcus of the rhesus monkey are important for the visuomotor transformations underlying actions directed toward objects.
Here, we show that anticipation of low-contrast stimuli, relative to high-contrast stimuli, is associated with increased prestimulus BOLD activity in the frontal eye field (FEF) and the posterior inferior frontal sulcus (IFS) but not in the intraparietal sulcus (IPS).
Children showed weaker activation in the intraparietal sulcus during all three tasks, in the left inferior frontal gyrus during EX and in occipital areas during MC.
Activation along the left intraparietal sulcus (IPS) was found when a low saliency stimulus had to be selected irrespective of its level.
Our results show that this role may be served by the intraparietal sulcus, which additively integrated a spatially specific activation gain in relation to spatial cue information with a spatially global activation gain in relation to feature cue information..
In contrast, following SD, reaction time benefits were associated with activation in the left intraparietal sulcus, a region associated with receptivity to stimuli at unexpected locations.
Although the inferior intraparietal sulcus (IPS) selects a fixed number of about four objects via their spatial locations, the superior IPS and the lateral occipital complex (LOC) encode the features of a subset of the selected objects in great detail (object shapes in this case).
Investigations in macaques and humans have shown that the anterior intraparietal sulcus (IPS) has an important function in the integration of information from tactile and visual object manipulation.
A conjunction analysis identified supramodal and material-unspecific activations within the medial and superior frontal gyrus and the superior parietal lobe including the intraparietal sulcus.
Abstract Within the parietal cortex, the temporo-parietal junction (TPJ) and the intraparietal sulcus (IPS) seem to be involved in both spatial and nonspatial functions: Both areas are activated when misleading information is provided by invalid spatial cues in Posner's location-cueing paradigm, but also when infrequent deviant stimuli are presented within a series of standard events.
Research in the attentional domain has shown that superior parietal lobe (SPL) regions along the intraparietal sulcus are implicated in the voluntary orienting of attention to relevant aspects of the environment, whereas inferior parietal lobe (IPL) regions at the temporo-parietal junction mediate the automatic allocation of attention to task-relevant information. By reviewing the existing fMRI literature, we show that the posterior intraparietal sulcus of SPL is consistently active when the need for top-down assistance to memory retrieval is supposedly maximal, e.g., for memories retrieved with low vs.
Activation of the posterior superior temporal sulcus/superior temporal gyrus region was found in both hemispheres during recognition of transitive and intransitive gestures, and in the right hemisphere during the control condition; the middle temporal gyrus showed activation in the left hemisphere when subjects recognized transitive and intransitive gestures; activation of the left inferior parietal lobe and intraparietal sulcus (IPS) was mainly observed in the left hemisphere during recognition of the three conditions.
The fMRI conjunction analysis revealed overlapping activation for both S-states in primary motor cortex, premotor cortex, and the supplementary motor area as well as in the intraparietal sulcus, cerebellar hemispheres, and parts of the basal ganglia.
The analysis of the interaction between STIMULI and TASK, which isolates the neural mechanism underlying BSD, revealed an activation of left posterior intraparietal sulcus (IPS) when the distance between body parts was evaluated.
Previous functional MRI data revealed the right dorsolateral prefrontal cortex and the region of the left intraparietal sulcus (IPS) to be involved in the perception of emotionally negative stimuli. An interference with emotion processing was found with transcranial magnetic stimulation above the dorsolateral prefrontal cortex 200-300 ms and above the left intraparietal sulcus 240/260 ms after negative stimuli.
Two bilateral PPL areas lying along the intraparietal sulcus (IPS) were stimulated with rTMS.
Our results provide new information that the anterior intraparietal sulcus (IPS) is involved in tasks requiring a magnitude processing with symbolic (numbers) and nonsymbolic (locations) stimuli.
Participants had to compare the numerosity of flashed dot sequences or the duration of single dot displays before and after 15 min of 1 Hz rTMS over one of three sites (the left or right intraparietal sulcus (IPS), or the vertex chosen as a control site).
We report a case of a patient, AD, who suffered from acalculia following an infarct restricted to the left IPS (intraparietal sulcus).
Interestingly, regions more activated in children relative to adults were centred on bilateral supramarginal gyrus (SMG) and lateral portions of the anterior intraparietal sulcus (IPS), further extending to adjacent right post- and precentral gyrus, the latter of which has been reported to support grasping previously (Simon et al., 2002).
In one area, the lesion-volume map overlapped with the activity map obtained in healthy volunteers: the lower bank of the middle third of the right intraparietal sulcus (IPS).
The left superior parietal lobule, intraparietal sulcus, bilateral premotor cortices and right cerebellum were activated during both visual and tactile motion discrimination.
This study manipulated the grouping between shapes and found that fMRI response from the inferior intraparietal sulcus (IPS) was higher for the disconnected (ungrouped) than for the connected (grouped) shapes in a task in which observers simply watched the displays and performed a simple image motion jitter detection task.
Our results suggest that there are separate but partially overlapping neural circuits for the processing of ordinal and cardinal numbers, irrespective of the presence of an NF, but a core region in the anterior intraparietal sulcus representing (cardinal) number meaning appears to be activated autonomously, irrespective of task.
Interestingly, our data show that the CDC illusion is preceded by an enhanced activation that is most dominantly present in the ventral intraparietal sulcus.
Previous WS studies have identified functional and structural abnormalities in the hippocampal formation, prefrontal regions crucial for amygdala regulation and social cognition, and the dorsal visual stream, notably the intraparietal sulcus (IPS).
Posterior parietal cortex (PPC), including intraparietal sulcus, posterior cingulate, and the orbitofrontal cortex displayed correlations with the speed of attentional shifts that were sensitive not just to motivational state but also to the motivational value of the target.
We identified a network of primary and secondary cortical areas: (I) regions that presumably receive direct proprioceptive thalamic input such as areas 3a, 2, S2 and the parieto-insular vestibular cortex (PIVC), (II) foci in the intraparietal sulcus, motor and premotor areas, and the frontal eye field (FEF).
The results of both passive and active experiments reveal that the extraction of 3D SfT involves the bilateral caudal inferior temporal gyrus (caudal ITG), lateral occipital sulcus (LOS) and several bilateral sites along the intraparietal sulcus.
Shape encoding involved a large sensorimotor network including the primary (SI) and secondary (SII) somatosensory cortex, the anterior part of the intraparietal sulcus (IPA) and of the supramarginal gyrus (SMG), regions previously associated with somatosensory shape perception.
Tasks tapping g(f) activate a network of brain regions including the lateral prefrontal cortex (LPFC), the presupplementary motor area/anterior cingulate cortex (pre-SMA/ACC), and the intraparietal sulcus (IPS).
The posterior part of the intraparietal sulcus (IPS), the putative human homolog of caudal-IPS, was found to be primarily involved in representing the visual location of the tools, whereas more anterior regions, the human homologs of medial intraparietal area and anterior intraparietal, primarily encoded the identity of the contralateral acting-hand.
A number of areas exhibited retinotopic activations, including full or partial visual field representations in occipital cortex, the precuneus, motion-sensitive temporal cortex (extending into the superior temporal sulcus), the intraparietal sulcus, and the vicinity of the frontal eye fields in frontal cortex.
Using fMRI, we found that activity in the right intraparietal sulcus (IPS) mirrored the behavioural interaction in saccade latencies.
One is putative area VIP in the anterior portion of the intraparietal sulcus.
Short trains of TMS pulses (12 Hz) were applied to a site overlying the right intraparietal sulcus/inferior parietal lobe while subjects performed either object identification tasks (i.e., picture-word verification and categorizing objects as natural or manufactured) or object orientation judgment tasks (i.e., picture-arrow verification and deciding whether an object was rotated clockwise or counterclockwise).
During the delay between the cue and target, we observed significant transient activity in right frontal eye field and right occipital-parietal junction, and significant sustained activity in right ventral intraparietal sulcus and right dorsolateral and anterior prefrontal cortex..
(2) A parieto-occipital brain region including the precuneus, superior parietal lobule, posterior part of the intraparietal sulcus (IPS), and cuneus was relatively deactivated during saccades performed with eyes closed but not during saccades with eyes open or when looking straight ahead.
Here, we perform an integrative experimental and computational analysis to determine the effective balance between the superior frontal sulcus (SFS) and intraparietal sulcus (IPS) and their putative role(s) in protecting against distracters.
A voxel-based analysis revealed a similar pattern in clusters of voxels located within VOTC, frontal eye fields, superior colliculi, intraparietal sulcus, and inferior frontal gyrus.
Finally, a region in the caudal intraparietal sulcus (cIPS) responded more strongly to both stereo versus motion and to stereo surfaces versus random stereo (but not to motion surfaces vs.
The activated regions consistently include the intraparietal sulcus in the lateral parietal cortex and the precuneus in the medial parietal cortex.
Abstract Previous imaging work has shown that the superior temporal sulcus (STS) region and the intraparietal sulcus (IPS) are specifically activated during the passive observation of shifts in eye gaze [ Pelphrey, K.
These steps activated distinct areas: Decision and Preparation selectively activated the left posterior parietal cortex (left deep posterior intraparietal sulcus and left medial posterior intraparietal sulcus), whereas Execution activated only the right posterior parietal cortex (right medial posterior intraparietal sulcus).
Adult neuropsychological and neuroimaging research points to the intraparietal sulcus as a key region for the representation and processing of numerical magnitude. We show that, in children with pure DD, the right intraparietal sulcus is not modulated in response to numerical processing demands to the same degree as in typically developing children.
The lesions of patients who did versus did not show neglect improvement immediately after prisms provide an initial indication that lack of improvement may potentially relate to cortical damage in right intraparietal sulcus and white matter damage in inferior parietal lobe and middle frontal gyrus.
The medial wall of the intraparietal sulcus and adjacent intraparietal cortex was selectively recruited by the processing of meaningful upper limb movements, irrespective of whether these were object-related or not. Besides reach and grasp movements, the intraparietal sulcus may thus be involved in limb gesture processing, that is, in an important aspect of human social communication.
We found that the right MT+, precuneus, as well as areas located bilaterally along the dorsal part of the intraparietal sulcus and along the left posterior intraparietal sulcus were more active during self-motion perception than during object-motion.
The source of the N1a was previously localized in the intraparietal sulcus in the dorsal occipital cortex; N1p may represent a reactivation of area V3A and P2 reactivation of occipital visual areas including V1 due to top-down feedbacks.
Here we show that grouped shapes elicited lower functional MRI (fMRI) responses than ungrouped shapes in inferior intraparietal sulcus (IPS) even when grouping was task-irrelevant.
Based on the Simulation Framework, we hypothesized that the ACTION component depends on the primary motor and premotor cortices, that the MOTION component depends on the posterolateral temporal cortex, that the CONTACT component depends on the intraparietal sulcus and inferior parietal lobule, that the CHANGE OF STATE component depends on the ventral temporal cortex, and that the TOOL USE component depends on a distributed network of temporal, parietal, and frontal regions.
Instruction-related activation was greater for nogo versus saccade trials in right frontal eye field, middle frontal gyrus, intraparietal sulcus, and precuneus, which we attribute to a mixture of preparatory and task switching processes.
BACKGROUND: Neurophysiological studies showed that in macaques, grasp-related sensorimotor transformations are accomplished in a circuit connecting the anterior intraparietal sulcus (area AIP) with premotor area F5. The human anterior intraparietal sulcus (hAIPS) was more active for precise grasping than for whole hand grasp independently of stimulus size.
Individuals with Asperger's syndrome had bilateral abnormalities in the intraparietal sulcus that correlated with age, intelligence quotient, and Autism Diagnostic Interview-Revised social and repetitive behavior scores.
Previous studies have highlighted the role of the superior intraparietal sulcus (IPS) in storing single object features in visual short-term memory (VSTM), such as color, orientation, shape outline, and shape topology.
Based on their ability to improve on the task within a single scan session, subjects were separated into two groups: "learners" and "nonlearners." As learning progressed, learners showed progressively reduced activation in both visual cortex, including Brodmann's areas 18 and 19 and the fusiform gyrus, and several cortical regions associated with the attentional network, namely, the intraparietal sulcus (IPS), frontal eye field (FEF), and supplementary eye field.
This contrast revealed activity in a distributed frontoparietal cortical network, within which the levels of activity in right posteromedial parietal cortical foci [ right posterior intraparietal sulcus (pIPS) and right precuneus] significantly predicted individual acuity thresholds.
The results reveal only a single bilateral region in the cerebral cortex located in the intraparietal sulcus (IPS; Brodmann's area 40) exhibiting sustained activations during the execution of both motor and task sequences. Thus, our results reveal the central role of the bilateral intraparietal sulcus in high-order sequential cognition and suggest a major functional segregation within the frontoparietal network mediating action planning, with the frontal and parietal sector involved in processing the hierarchical and serial structure of action plans, respectively..
Compared to controls, children with DD show significantly reduced gray matter volume in the right intraparietal sulcus (IPS), the anterior cingulum, the left inferior frontal gyrus, and the bilateral middle frontal gyri.
Bilateral selectivity for shape, with overlap between modalities, was found in a dorsal set of parietal areas: the postcentral sulcus and anterior, posterior and ventral parts of the intraparietal sulcus (IPS); as well as ventrally in the lateral occipital complex.
The hypothesized circuit that was investigated here comprised initial integration of audiovisual speech by the middle superior temporal sulcus (STS), followed by recruitment of the intraparietal sulcus (IPS), followed by activation of Broca's area [ Miller, L.M., d'Esposito, M., 2005.
Mental rotation is accompanied by increased activity in the intraparietal sulcus and adjacent regions.
Abstract Previous imaging work has shown that the superior temporal sulcus (STS) region and the intraparietal sulcus (IPS) are specifically activated during the passive observation of shifts in eye gaze [ Pelphrey, K.
Electrophysiological recordings from monkeys, as well as functional imaging and neuropsychological work with humans, have suggested that a region in the anterior portion of the intraparietal sulcus (aIPS) is involved in prehensile movements.
RESULTS: As compared with control subjects, HD patients showed decreased activation in the left caudate nucleus and medial frontal and anterior cingulate gyri and increased activation in the right supplementary motor area and supramarginal gyrus and left intraparietal sulcus.
When the mixture was contrasted with the sum of its single components (CO(2)PEA-{CO(2)+PEA}), activations in integration centers (left superior temporal and right intraparietal sulcus) and in orbitofrontal areas (left medial and lateral orbitofrontal cortex) were detected.
On the other hand, the right lateral frontal eye field and bilateral intraparietal sulcus showed evidence of selective involvement in antisaccade generation.
Recent studies suggest that numbers activate a representation of their quantity within the intraparietal sulcus (IPS) automatically, that is, in tasks that do not require the processing of quantity.
The anterior intraparietal sulcus, and more specifically its horizontal segment (hIPS), is known to play a crucial role in the cognitive representation of numerical quantity.
An overlap between executed, observed, and imagined reaching activations was found in dorsal premotor cortex as well as in the superior parietal lobe and the intraparietal sulcus, in accord with our hypothesis.
High-intensity clicks activated wide areas of the cortex, namely, the frontal lobe (prefrontal cortex, premotor cortex, and frontal eye fields), parietal lobe (the region around the intraparietal sulcus, temporo-parietal junction, and paracentral lobule), and cingulate cortex.
Here we used transcranial magnetic stimulation (TMS) and functional magnetic resonance imaging (fMRI) concurrently, to show that stimulating right human intraparietal sulcus (IPS, at a site previously implicated in attention) elicits a pattern of activity changes in visual cortex that strongly depends on current visual context.
In addition, several regions, including dorsolateral prefrontal cortex and intraparietal sulcus, demonstrated material-nonspecific congruency effects.
The former include visuospatial long-term and working memory and the intraparietal sulcus, whereas the latter include the central executive component of working memory and the anterior cingulate cortex and lateral prefrontal cortex.
The human superior parietal cortex (SPC; Brodmann areas [ BA] 5 and 7) comprises the superior parietal lobule and medial wall of the intraparietal sulcus (mIPS) laterally and the posterior paracentral lobule and precuneus medially.
Reading repeated names elicited more activation than pronouns in the middle and inferior temporal gyri and intraparietal sulcus. The intraparietal sulcus activation suggests that this integration relies on brain regions used for spatial attention and perceptual integration..
Direct comparisons showed action knowledge, relative to functional knowledge, to activate a left frontoparietal network, comprising the intraparietal sulcus, the inferior parietal lobule, and the dorsal premotor cortex.
AG/intraparietal sulcus)..
In contrast, the anterior temporal lobe and intraparietal sulcus are activated by changes in acoustic scale across categories. The results imply that the human voice requires special processing of acoustic scale, whereas the anterior temporal lobe and intraparietal sulcus process auditory size information independent of source category..
Nonetheless, half trials evoked stronger activation on antisaccades than on prosaccades in the frontal eye field (FEF), supplementary eye field (SEF), left dorsolateral prefrontal cortex (DLPFC), anterior cingulate cortex (ACC), intraparietal sulcus (IPS), and precuneus.
A frontoparietal network included the dorsolateral prefrontal cortex and intraparietal sulcus.
areas within the intraparietal sulcus), SMA and primary motor cortex were correlated with the extent of motor dysfunction.
Two macaques (M1 and M2) were implanted with recording chambers over the right intraparietal sulcus and with search coils for recording three-dimensional eye and head movements.
Encoding of hand movements activated somatosensory areas, superior parietal lobe (dorsodorsal stream), anterior intraparietal sulcus (aIPS) and adjoining areas (ventrodorsal stream), premotor cortex, and occipitotemporal cortex (ventral stream).
CONCLUSION: The present findings and a review of the literature suggest that: (i) a postcentral gyrus lesion can yield graphemic distortion (somesthetic dysgraphia), (ii) abnormal grapheme formation and impaired character recall are associated with lesions surrounding the intraparietal sulcus, the symptom being more severe with the involvement of the inferior parietal, superior occipital and precuneus gyri, (iii) disordered writing stroke sequences are caused by a damaged anterior intraparietal area..
We found that in the left hemisphere both the intraparietal sulcus and the frontal eye field showed a pattern of activity consistent with sensorimotor transformation - a transition from activity reflecting the direction of the stimulus to that representing the saccadic goal. These findings suggest that sensorimotor transformation is the product of coordinated activity across the intraparietal sulcus and frontal eye field, key components of a cortical network for saccadic generation..
'Unitary' control modulations were temporally dissociated into (1) shared tonic components involving medial and lateral prefrontal cortex, striatum, cerebellum and superior parietal cortex, assumed to govern enhanced top-down context processing, monitoring and sustained attention throughout task periods and (2) stimulus-synchronous phasic components encompassing posterior intraparietal sulcus, hypothesized to support dynamic shifting of the 'focus of attention' among internal representations.
The magnitude of intraparietal sulcus activation and memory capacity after normal sleep were highly correlated.
These maps are located along the medial bank of the intraparietal sulcus (IPS) and are revealed by direct visual stimulation during functional magnetic resonance imaging, allowing these parietal regions to be routinely and reliably identified simultaneously with occipital visual areas.
Relative to correct Novelty decisions, correct Recency decisions elicited greater activation in a network of left-lateralized regions, including frontopolar and dorsolateral prefrontal cortex and intraparietal sulcus.
Among the critical 'nodes' of the network, an area centered within the left intraparietal sulcus (IPS) is thought to be related to the motoric representations associated with familiar tools and their usage.
Herein, we review and make parallels between experiments in monkeys and humans on a broad array of motor as well as non-motor tasks in order to characterize the specific contribution of a region in the parietal lobe, the anterior intraparietal sulcus (aIPS).
Studies in macaque monkeys have demonstrated a functional specialisation around the intraparietal sulcus (IPS) with a more medial representation of hand movements ("parietal reach region") and a more lateral representation of saccadic eye movements (lateral intraparietal area, LIP). MRI scans showed bilateral line-shaped hemorrhagic lesions, restricted to the cortex at the medial banks of the intraparietal sulcus, but leaving its lateral banks largely intact.
The opposite contrast of pantomimed versus actual tool use revealed differential activation only in the left intraparietal sulcus in a corresponding region-of-interest analysis.
A network involving frontal and parietal regions showed increased activation for the phrased condition with the orbital part of left inferior frontal gyrus presumably reflecting working memory aspects of the temporal integration between phrases, and the middle frontal gyrus and intraparietal sulcus probably reflecting attention processes.
In monkeys, areas in the intraparietal sulcus (IPS) play a crucial role in visuospatial information processing.
Right hemisphere stimulation over the posterior termination of the intraparietal sulcus (IPSp) broadened and shifted the distribution of second-saccade endpoints, but only when the first-saccade was directed into the contralateral hemifield.
Rising intensity sounds produced neural activity in the amygdala, which was accompanied by activity in intraparietal sulcus, superior temporal sulcus, and temporal plane.
We used functional magnetic resonance imaging to assess the degree of effector preference at the population level, focusing on topographically organized regions in the human PPC [ visual area V7, intraparietal sulcus 1 (IPS1), and IPS2].
Difference judgments based on visual (color, form, and motion) cues and auditory cues show that a population of neurons in the posterior banks of the intraparietal sulcus (PIPS) is consistently activated for perceptual judgment across visual attributes and sensory modalities, suggesting that those neurons in PIPS are associated with perceptual judgment..
The contrast between TAF and non-TAF conditions revealed significant activations; the supramarginal gyrus, the prefrontal area, the anterior insula, the superior temporal area and the intraparietal sulcus in the right hemisphere, but only the premotor area in the left hemisphere.
We show that portions of parietofrontal circuits, including intraparietal sulcus and left dorsal premotor cortex, are systematically involved in programming motor responses, their activity being indifferent to the presence of earlier motor plans.
Previous imaging studies determined the intraparietal sulcus (IPS) as a central area for numerical processing [ 4-11].
Large pitch changes were associated with right hemisphere supratemporal activations as well as widespread bilateral activations in the frontal lobe and along the intraparietal sulcus.
After a half-hour of daily training for 4 weeks with repetitive passive and active arm movements, cerebral activation increased in the pre-SMA and SMA, ipsilateral primary sensory cortex and intraparietal sulcus, and contralateral cerebellum in parallel with functional improvements of the upper limb. Areas common to both analyses included the SMA, pre-SMA, primary sensory cortex, intraparietal sulcus, and cerebellum.
Some neuroimaging studies have shown that the intraparietal sulcus region is critically involved in mental rotation. Results provided clear support for the prediction, demonstrating overlap between dorsal object-sensitive regions in ventral-caudal intraparietal sulcus (vcIPS) and an adjacent dorsal occipital area and the regions that are activated during mental rotation but not during saccades.
A higher level of mapping was observed in the intraparietal sulcus (IPS), inferior parietal lobule (IPL), and inferior frontal gyrus (IFG).
Participants made fewer binding errors after 1 Hz rTMS of the right intraparietal sulcus (IPS), while basic perception of features (color and shape) was unaffected.
Conjunction and functional connectivity analyses demonstrated that the cerebral areas activated by all three experimental tasks are the left frontopolar cortex, bilateral dorsolateral prefrontal and premotor cortex, bilateral intraparietal sulcus, right inferior parietal lobule and cerebellum.
In the monkey brain, different groups of cells in the anterior-lateral bank of the intraparietal sulcus (area AIP) are differentially active for various hand configurations during grasping of differently shaped objects. Visually guided grasping studies in humans suggest the anterior intraparietal sulcus (aIPS) as the homologue of macaque area AIP, but leave unresolved the question of whether activity in human aIPS reflects the relationship between object size and grasp configuration, as in macaques.
Consistent with prior studies, the incongruent arrow condition recruited activity in bilateral midfrontal gyrus, right inferior frontal gyrus, bilateral intraparietal sulcus, and the anterior cingulate relative to the congruent arrow condition in neurotypical participants.
We investigated whether left and/or right intraparietal sulcus (IPS) contributed to the AB bottleneck using transcranial magnetic stimulation (TMS).
Results showed that both addition and multiplication were supported by a broad neural system that involved regions within SMA, precentral gyrus, intraparietal sulcus, occipital gyri, superior temporal gyrus, and middle frontal gyrus, as well as some subcortical structures. Nevertheless, addition problems elicited more activation in the intraparietal sulcus and middle occipital gyri at the right hemisphere, and superior occipital gyri at both hemispheres, whereas multiplication had more activation in precentral gyrus, supplementary motor areas, and posterior and anterior superior temporal gyrus at the left hemisphere.
Functional neuroimaging results, studies on patients with posterior parietal cortex (PPC) lesions, and single-unit recordings in the lateral intraparietal sulcus of primates indirectly suggest that the PPC might be a potential locus of visual stability through its involvement with spatial remapping.
Our data revealed a functional dissociation between 2 juxtaposed posterior parietal regions: one in the superior parietal lobule (SPL) and another in the intraparietal sulcus (IPS).
Our results demonstrate that preparatory attentional allocation following a cue to the upcoming level of conflict is mediated by a network involving Dorsolateral Prefrontal Cortex (DLPFC) and the intraparietal sulcus (IPS).
The most extensive cortical activations were found in the right intraparietal sulcus (IPS), the anterior cingulate cortex (ACC), and the right lateral prefrontal cortex (PFC).
In this functional magnetic resonance imaging study, we localized areas in human intraparietal sulcus (IPS) and lateral occipital complex (LOC) that represent nearby visual space with respect to the hands (perihand space), by contrasting the response to a ball moving near-to versus far-from the hands.
This study explored the validity of an attentional account for the involvement of the left intraparietal sulcus (IPS) in visual STM tasks.
Reaching in central vision involves a restricted network, including the medial intraparietal sulcus (mIPS) and the caudal part of the dorsal premotor cortex (PMd).
Activation of the horizontal segment of the intraparietal sulcus (hIPS) has been observed in various number-processing tasks, whether numbers were conveyed by symbolic numerals (digits, number words) or by nonsymbolic displays (dot patterns).
It is well established that the intraparietal sulcus (IPS) plays an important role in the processing and representation of numerical magnitude.
It has been widely argued that the intraparietal sulcus (IPS) is involved in tasks that evoke representations of numerical magnitude, among other cognitive functions.
Although subjects listened to the music without performing any movements, activation was found bilaterally in the frontoparietal motor-related network (including Broca's area, the premotor region, the intraparietal sulcus, and the inferior parietal region), consistent with neural circuits that have been associated with action observations, and may constitute the human mirror neuron system.
This was paralleled by reduced BOLD signal in the right dentate nucleus, the left sensorimotor cortex, and the left intraparietal sulcus.
Among these regions, only activity within the right intraparietal sulcus predicts the accuracy with which observed procedures are subsequently performed.
Sensitivity to justice issues was associated with greater activation of the left intraparietal sulcus, whereas sensitivity to care issues was associated with greater activation of the ventral posterior cingulate cortex, ventromedial and dorsolateral prefrontal cortex, and thalamus.
However, adults exhibit stronger activation in the left intraparietal sulcus compared to children.
DATA SYNTHESIS: Results from a number of studies converge on the hypothesis that hypoperfusion and/or infarct of right angular gyrus and intraparietal sulcus can cause viewer-centered neglect, whereas hypoperfusion and/or infarct of right superior temporal gyrus can lead to left stimulus-centered neglect.
Although sub-regions in the human superior parietal lobe and intraparietal sulcus contribute to vision-for-action and spatial functions, more inferior parietal regions have distinctly non-spatial attributes that are neither conventionally 'dorsal' nor conventionally 'ventral' in nature..
small saccade blocks revealed robust activity in the oculomotor system, particularly within the frontal eye fields (FEF), intraparietal sulcus (IPS), and superior colliculi regardless of the background image.
The following primary sulci were then visible until ED 120: the superior temporal sulcus on ED 90; the intraparietal sulcus, lunate sulcus, inferior occipital sulcus, and arcuate sulcus on ED 100; and the principle sulcus on ED 110; the occipitotemporal sulcus, anterior middle temporal sulcus, and superior postcentral dimple on ED 120.
FMRI results revealed stronger activation during the MI than LI condition in brain regions involved in top-down control (inferior and medial prefrontal cortex, intraparietal sulcus), and in posterior, object-sensitive brain regions (ventral and dorsal occipitotemporal, and occipitoparietal cortex).
Functional brain imaging studies with human adults have repeatedly revealed that bilateral regions of the intraparietal sulcus are correlated with various numerical and mathematical skills. Although behavioral performance was similar across groups, in comparison to the group of children the adult participants exhibited greater effects of numerical distance on the left intraparietal sulcus.
Cognitive Neuropsychology, 20, 487-506] state that mathematical performance is made possible by two functionally and anatomically distinct subsystems of number processing: a verbal system located in the angular gyrus, which underlies the retrieval of arithmetic facts, and a quantity system located in the intraparietal sulcus, which subserves operations that involve semantic manipulations of quantity. This provides evidence for a specific deficit in the quantity subsystem in children with VCFS, suggesting underlying abnormalities in the intraparietal sulcus..
RESULTS: The points studied were the anterior sylvian point, the inferior rolandic point, the intersection of the inferior frontal sulcus with the precentral sulcus, the intersection of the superior frontal sulcus with the precentral sulcus, the superior rolandic point, the intersection of the intraparietal sulcus with the postcentral sulcus, the superior point of the parieto-occipital sulcus, the euryon (the craniometric point that corresponds to the center of the parietal tuberosity), the posterior point of the superior temporal sulcus, and the opisthocranion, which corresponds to the most prominent point of the occipital bossa.
The anterior part of the human intraparietal sulcus is known to be involved in visually guided grasping.
Lesion and functional imaging studies in humans have suggested that the dorsolateral prefrontal cortex (DLPFC), ventrolateral prefrontal cortex (VLPFC), and intraparietal sulcus (IPS) are involved in orienting attention.
Multivariate, partial least-squares analysis supported a MS/DB-dependent functional network: MS/DB activity covaried with activity in areas important to selective attention, including intraparietal sulcus, and memory that are direct cholinergic efferents of the MS/DB, including the hippocampus, as well as the ventrolateral prefrontal cortex, implicated in PI resolution.
We found that temporal and spatial enumeration processes engaged different populations of neurons in the intraparietal sulcus of behaving monkeys.
Moreover, activity in the intraparietal sulcus was modulated by subjects' own hand position: a larger incongruence in orientation between the subjects' hand and the stimulus hand led to a selective increase in intraparietal activity.
RESULTS: Children with DD showed greater inter-individual variability and had weaker activation in almost the entire neuronal network for approximate calculation including the intraparietal sulcus, and the middle and inferior frontal gyrus of both hemispheres. In particular, the left intraparietal sulcus, the left inferior frontal gyrus and the right middle frontal gyrus seem to play crucial roles in correct approximate calculation, since brain activation correlated with accuracy rate in these regions.
Frontal and supplementary eye fields, anterior cingulate cortex, intraparietal sulcus, and precuneus, exhibited surprisingly similar activation patterns for prosaccade and nogo responses, suggesting that BOLD signal in cortical saccade regions might predominantly reflect visual detection and attention processes rather than saccade generation or inhibition.
Across groups, the "hard choice > no choice" contrast revealed significant effects in the ventrolateral prefrontal cortex, dorsolateral prefrontal cortex (DLPFC), dorsal anterior cingulate cortex, and areas surrounding the intraparietal sulcus (IPS).
Interestingly, crossmodal effects during audiovisual speech and object recognition have been found in the superior temporal sulcus, while crossmodal effects during the execution of spatial tasks have been found over the intraparietal sulcus, suggesting an underlying "what/where" segregation. Task-related differences in BOLD response were observed in the right intraparietal sulcus and in the left superior temporal sulcus, providing a direct confirmation of the "what-where" functional segregation in the crossmodal audiovisual domain..
The activity of the right intraparietal sulcus (IPS) was significantly larger than that for the left IPS at latencies around 196 ms irrespective of the target's presence or not.
During a choice saccade task in which one target is selected among many alternatives based on the color of a cue in the center, the frontal eye fields (FEF) and intraparietal sulcus (IPS) were activated.
It is suggested that this brain area, the left intraparietal sulcus, subserves various comparison processes by representing various quantities on an amodal magnitude scale..
Repetitive transcranial magnetic stimulation (rTMS) was applied over inferior parietal areas and the adjacent intraparietal sulcus (IPS) while subjects solved double-digit addition tasks.
Areas activated included primary motor cortex, dorsal premotor cortex, anterior intraparietal sulcus, and caudal supplementary motor area, regions that are also involved in some hand movement illusions and motor imagery in normals.
Although a role of the intraparietal sulcus (IPS) in grasping is becoming evident, the specific contribution of regions within the IPS remains undefined.
In the single-subject analysis, whereas the first two of the above three areas were found to be crucial for writing in all individuals, an interindividual inconsistency of involvement with writing was observed in three areas: the lower part of the anterior limb of the left supramarginal gyrus (60% involved); the right frontal region (47%); and the right intraparietal sulcus (47%)..
The fMRI experiment showed that among the frontoparietal regions involved in retrieval success, the inferior frontal gyrus and intraparietal sulcus were crucial to conscious recollection because the activity of these regions was influenced by the depth of memory at encoding.
Fibers from area 8Av course via FOF and SLF II, merging in the white matter of the inferior parietal lobule (IPL) and terminating in the caudal intraparietal sulcus (IPS).
This was particularly pronounced for regions in bilateral intraparietal sulcus (IPS), which also showed greater functional coupling with occipital cortex specifically on bilateral trials that required selection plus some repetition-suppression effects when target side was repeated, but again only on bilateral trials requiring selection.
Outside the basal ganglia, dystonic patients showed task-related overactivity in visual cortical areas, left anterior insula and right intraparietal sulcus, but not in the primary or secondary sensory cortex.
We hypothesized that a region within the intraparietal sulcus (IPS) would be engaged in orientation processing, regardless of the sensory modality.
Areas around the horizontal part of the intraparietal sulcus (hIPS) have repeatedly been reported to participate in processing numerical magnitude.
Neuroimaging studies in healthy subjects have identified the superior parietal cortex and intraparietal sulcus as important structures involved in visual search.
Most importantly, despite controlling for differences in spatial short-term memory capacity, we observed a tight relationship between mental rotation proficiency and white matter organization near the anterior part of the intraparietal sulcus.
The present study used fMRI to investigate neural substrates of number sequence recitation, focusing on the intraparietal sulcus (IPS) and perisylvian areas.
Furthermore, using this characterization to classify decisions as exploratory or exploitative, we employ functional magnetic resonance imaging to show that the frontopolar cortex and intraparietal sulcus are preferentially active during exploratory decisions.
A mostly left-hemispheric network consisting of left intraparietal sulcus, inferior and superior parietal lobule, bilateral precuneus, middle frontal gyri including superior frontal sulci, and middle occipital gyri displayed BOLD responses to cues that increased linearly with more precise spatial cueing, indicating engagement by top-down spatial selective attention.
Functional neuroimaging studies of numerical cognition have repeatedly associated activation of the intraparietal sulcus (IPS) with number processing.
Neural responses to objects associated with familiar relative to unfamiliar places in pPCC, but not in the retrosplenial cortex, were negatively correlated with task-related activation (common over all objects) in the right anterolateral prefrontal cortex and the left intraparietal sulcus.
Furthermore, activation that was driven by both the task and the strength of the Müller-Lyer illusion was observed in right intraparietal sulcus, thus arguing in favor of an interaction of illusory information with the top-down processes underlying visuospatial judgments in right parietal cortex..
One of the most consistently activated regions during verbal short-term memory (STM) tasks is the left intraparietal sulcus (IPS).
In a previous study, we identified three cortical areas in human posterior parietal cortex that exhibited topographic responses during memory-guided saccades [ visual area 7 (V7), intraparietal sulcus 1 (IPS1), and IPS2], which are candidate homologs of macaque parietal areas such as the lateral intraparietal area and parietal reach region.
The reports of graded perceptual clarity were reflected in graded neural activity in a network comprising the precentral gyrus, intraparietal sulcus, basal ganglia and the insula.
Haptic shape-selective regions, identified on a contrast between the haptic shape and texture conditions in individual subjects, were found bilaterally in the postcentral sulcus (PCS), multiple parts of the intraparietal sulcus (IPS) and the lateral occipital complex (LOC).
The intraparietal sulcus (IPS) is known to respond selectively to symbolic numerical stimuli such as Arabic numerals.
After training, neural activity emerged in regions associated with the motion (left middle temporal gyrus) and manipulation (left intraparietal sulcus and premotor cortex) of common tools, whereas activity became more focal and selective in regions representing their visual appearance (fusiform gyrus).
Functional, connectional, and architectonic data have indicated that area 7 is comprised of several distinct sectors located in the lateral bank of the intraparietal sulcus and on the IPL cortical convexity. All areas extend dorsally up to the lateral bank of the intraparietal sulcus, for about 1-2 mm.
The human intraparietal sulcus (IPS) is implicated in processing symbolic number information and possibly in nonsymbolic number information.
For the choice contrast, activation was found in the rostral cingulate zone (RCZ) as well as the superior parietal lobule and the posterior part of the intraparietal sulcus.
In contrast, increased activation was consistently observed in visual areas V3A and V4v, higher-level cortex in the intraparietal sulcus, posterior superior temporal sulcus, and the ventral occipital-temporal region, as well as the pulvinar.
The parietal region that was active during the writing of single letters spanned the border between the parietal superior and inferior lobuli Brodmann area (BA 2, 40), deep in the intraparietal sulcus, with a surprising right-sided dominance.
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